hermes stroke study | thrombectomy stroke hermes stroke study The study investigators established the Highly Effective Reperfusion Evaluated in Multiple Endovascular Stroke Trials (HERMES) collaboration to undertake meta-analysis of pooled individual patient data.
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0 · thrombectomy stroke
1 · thrombectomy after ischaemic stroke
2 · Hermes meta analysis
3 · Hermes collaboration stroke
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thrombectomy stroke
In these trials, patients with acute ischaemic stroke caused by occlusion of the proximal anterior artery circulation were randomly assigned to receive either endovascular thrombectomy within 12 h of symptom onset or standard care (control), with a primary . Our study provides clear evidence that in clinical practice, endovascular therapy . In these trials, patients with acute ischaemic stroke caused by occlusion of the proximal anterior artery circulation were randomly assigned to receive either endovascular thrombectomy within 12 h of symptom onset or standard care (control), with a primary outcome of reduced disability on the modified Rankin Scale (mRS) at 90 days.
Our study provides clear evidence that in clinical practice, endovascular therapy for stroke should not be withheld on the basis of advanced age, moderately extensive early ischaemic changes on baseline CT, and moderate or severe clinical deficit. We aimed to assess whether the treatment effect of EVT on improved functional outcome in patients with ICA occlusions from the highly effective reperfusion evaluated in multiple endovascular stroke trials (HERMES) collaboration is maintained in patients with ICA‐I occlusion.
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The study investigators established the Highly Effective Reperfusion Evaluated in Multiple Endovascular Stroke Trials (HERMES) collaboration to undertake meta-analysis of pooled individual patient data. The HERMES trial pooled data from five randomized trials of endovascular thrombectomy for ischemic stroke due to large-vessel occlusions. It found that earlier treatment was associated with better outcomes, but the benefit declined after 7.3 hours.
In these trials, patients with acute ischaemic stroke caused by occlusion of the proximal anterior artery circulation were randomly assigned to receive either endovascular thrombectomy within 12 h of symptom onset or standard care (control), with a primary outcome of reduced disability on the modifi ed Rankin Scale (mRS) at 90 days. We analyzed data from the highly effective reperfusion evaluated in multiple endovascular stroke trials (HERMES) collaboration, which performed an individual patient data meta‐analysis of 7 randomized controlled trials conducted between 2010 and 2017 assessing the benefit of EVT compared to medical management in patients with anterior . This study showed that the HERMES-24 score was at least comparable and, in some cases, superior to the previously established scores including POST score, incorporating final infarct volume, to predict good functional outcomes after EVT.
Updates to European and North American guidelines 3–5 for acute stroke management have already reflected the findings of these trials by recommending endovascular thrombectomy in suitable patients, conclusions supported by the HERMES analysis.The landmark five trials from the HERMES collaboration that led to changes in acute ischaemic stroke care in 2015 focused on patients with stroke in the proximal anterior circulation. 4 However, an estimated 20% of strokes affect the posterior circulation, where the predominant supply is the basilar artery. Strokes secondary to basilar artery . In these trials, patients with acute ischaemic stroke caused by occlusion of the proximal anterior artery circulation were randomly assigned to receive either endovascular thrombectomy within 12 h of symptom onset or standard care (control), with a primary outcome of reduced disability on the modified Rankin Scale (mRS) at 90 days. Our study provides clear evidence that in clinical practice, endovascular therapy for stroke should not be withheld on the basis of advanced age, moderately extensive early ischaemic changes on baseline CT, and moderate or severe clinical deficit.
We aimed to assess whether the treatment effect of EVT on improved functional outcome in patients with ICA occlusions from the highly effective reperfusion evaluated in multiple endovascular stroke trials (HERMES) collaboration is maintained in patients with ICA‐I occlusion.
The study investigators established the Highly Effective Reperfusion Evaluated in Multiple Endovascular Stroke Trials (HERMES) collaboration to undertake meta-analysis of pooled individual patient data. The HERMES trial pooled data from five randomized trials of endovascular thrombectomy for ischemic stroke due to large-vessel occlusions. It found that earlier treatment was associated with better outcomes, but the benefit declined after 7.3 hours.In these trials, patients with acute ischaemic stroke caused by occlusion of the proximal anterior artery circulation were randomly assigned to receive either endovascular thrombectomy within 12 h of symptom onset or standard care (control), with a primary outcome of reduced disability on the modifi ed Rankin Scale (mRS) at 90 days. We analyzed data from the highly effective reperfusion evaluated in multiple endovascular stroke trials (HERMES) collaboration, which performed an individual patient data meta‐analysis of 7 randomized controlled trials conducted between 2010 and 2017 assessing the benefit of EVT compared to medical management in patients with anterior .
This study showed that the HERMES-24 score was at least comparable and, in some cases, superior to the previously established scores including POST score, incorporating final infarct volume, to predict good functional outcomes after EVT. Updates to European and North American guidelines 3–5 for acute stroke management have already reflected the findings of these trials by recommending endovascular thrombectomy in suitable patients, conclusions supported by the HERMES analysis.
thrombectomy after ischaemic stroke
Hermes meta analysis
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hermes stroke study|thrombectomy stroke
